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MFI Features and Benefits

Features and benefits for the expressed needs of the pharmaceutical industry

In the field of particle-analysis, few technologies can match Micro-Flow Imaging’s comprehensive technical specifications. MFI is a technology of choice that provides novel and unique insight for establishing the signature and control of particle populations. Compared with traditional technologies such as light obscuration or size exclusion chromatography, MFI has been demonstrated to identify trend changes in particle populations that often go undetected, and it is far more sensitive to highly transparent particles.  In fact, particle counting using MFI technology is proven to be the most sensitive method to observe and quantify protein aggregation. 

ProteinSimple designed MFI to meet the expressed needs of the pharmaceutical industry. It is equipped with exactly the features and benefits our clients need. For example, it:

  • 21 CFR Part 11 compliant,
  • Qualified and validated by industry
  • Automated sample delivery ensures consistency while providing unattended operation.

MFI’s features and benefits do not end there.

  • Easy to use, scalable and robust
  • Enables rapid candidate selection
  • Greatly improves process optimization and control
  • Designed for cGMP environments
  • Helps characterize any variances between comparability studies
  • Ideal for advanced diagnostics of particle deviances in a controlled process
  • Analyzes samples fifty times smaller than those required by current compendial methods
  • Meets the latest requirements from the United States Food and Drug Administration for the characterization and quantification of sub-visible aggregates and particulates

Science supported by experts

MFI’s reputation as a market-leading technology has been documented in a series of articles and studies in some of the pharmaceutical industry’s most revered peer-reviewed publications. Of these reviews, we are proudest of the praise we received from the Journal of Pharmaceutical Studies. In volume 100(2): 492-503, the study’s authors[1]  referred to MFI as “the most sensitive technique available for the detection of aggregated protein.

See how MFI’s features can yield proven benefits for your systems and processes. Contact Us today to arrange an on-site MFI demonstration.

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